Lipton D S, Brewington V, Smith M
National Development and Research Institutes, Inc., New York, New York.
J Subst Abuse Treat. 1994 May-Jun;11(3):205-15. doi: 10.1016/0740-5472(94)90077-9.
Anecdotal studies have reported acupuncture alleviating the severity of withdrawal symptoms associated with cocaine abuse. The efficacy of auricular (ear) acupuncture in reducing cocaine/crack craving and consumption was examined via a single-blind, placebo experiment. One hundred and fifty individuals seeking treatment for cocaine/crack abuse were randomly assigned to receive either experimental or placebo acupuncture treatments. Treatments were provided in an outpatient setting for a one-month period. Placebo treatments involved acupuncture at ear locations not used for drug treatment. Subjects provided urine specimens for drug content analysis after each acupuncture session. Urinalysis results over the one-month study period favored the experimental group. Experimental subjects in treatment over 2 weeks had significantly lower cocaine metabolite levels relative to placebo subjects in treatment for a comparable period. Treatment retention with both groups was similar. Relative to pretreatment usage, a significant decrease in cocaine consumption was reported by both groups. Self-report outcomes did not indicate significant between-groups differences.
轶事性研究报告称,针灸可减轻与可卡因滥用相关的戒断症状的严重程度。通过单盲、安慰剂实验,研究了耳针在减少对可卡因/强效纯可卡因的渴望及使用方面的疗效。150名寻求可卡因/强效纯可卡因滥用治疗的个体被随机分配接受实验性或安慰剂针灸治疗。治疗在门诊环境中进行,为期一个月。安慰剂治疗是在耳部未用于药物治疗的部位进行针刺。每次针灸治疗后,受试者提供尿液样本进行药物含量分析。在为期一个月的研究期间,尿液分析结果有利于实验组。与接受为期相当的治疗的安慰剂组受试者相比,接受治疗超过2周的实验组受试者的可卡因代谢物水平显著更低。两组的治疗保留率相似。与治疗前的使用情况相比,两组报告的可卡因使用量均显著减少。自我报告结果未显示出组间的显著差异。