Eulderink F
Afd. Pathologie, Diagnostisch Centrum Stichting Samenwerking Delftse Ziekenhuizen.
Ned Tijdschr Geneeskd. 1994 Aug 6;138(32):1618-22.
Checking the agreement of clinical and histopathological diagnoses of skin tumours sent in by general practitioners, surgeons and dermatologists in connection with the desirability of general practitioners removing skin tumours.
Retrospective descriptive study.
Diagnostic Centre SSDZ, Delft.
The clinical diagnoses on application forms and the histopathological diagnosis of skin tumours sent in during the first half of 1993 were compared. A discrepancy was scored if these diagnoses differed considerably. The discrepancies between the diagnoses were classified according to the clinical and histopathological diagnoses: malignant, premalignant or benign conditions.
Discrepancies were present in 31% (specimens from general practitioners), 32% (surgical specimens) and 17% (specimens from dermatologists). The longer differential diagnoses list of the dermatologists flattered this difference. In 9 out of 381 discrepancies a malignant tumour was underrated, in 37 a benign tumor had clinically been regarded as malignant. Dermatologists contributed more malignant and premalignant tumours than the other two groups, more often operated radically (punch biopsies excluded), and made fewer mistakes when they regarded a lesion as benign, but regarded more lesions incorrectly as malignant. Selection of specimens sent in for histopathology may have played a role in this connection.
General practitioners and surgeons had about the same number of discrepancies between clinical and histopathological diagnoses. The benefit of histopathological examination of skin tumours was clearly demonstrated.
结合全科医生切除皮肤肿瘤的可行性,核查全科医生、外科医生和皮肤科医生送来的皮肤肿瘤临床诊断与组织病理学诊断的一致性。
回顾性描述性研究。
代尔夫特诊断中心SSDZ。
比较了1993年上半年送来的皮肤肿瘤申请表上的临床诊断与组织病理学诊断。如果这些诊断存在显著差异,则记为有差异。根据临床和组织病理学诊断将诊断差异分为:恶性、癌前或良性情况。
差异出现在31%(全科医生送来的标本)、32%(外科标本)和17%(皮肤科医生送来的标本)中。皮肤科医生更长的鉴别诊断清单夸大了这种差异。在381例差异中,有9例恶性肿瘤被低估,37例良性肿瘤在临床上被视为恶性。皮肤科医生送来的恶性和癌前肿瘤比其他两组更多,更常进行根治性手术(不包括穿刺活检),在将病变视为良性时犯错较少,但将更多病变错误地视为恶性。送检进行组织病理学检查的标本选择可能在此方面起到了作用。
全科医生和外科医生在临床诊断与组织病理学诊断之间的差异数量大致相同。皮肤肿瘤组织病理学检查的益处得到了明确证明。