Nakashima S, Masuoka J, Tsuji T, Tabuchi K
Department of Neurosurgery, Saga Medical School.
No Shinkei Geka. 1994 Aug;22(8):781-4.
A rare case of mature pineal teratoma with interesting radiological findings in a 16-month-old infant is reported. The patient was referred to our clinic because of generalized convulsions. A CT scan showed marked hydrocephalus and a low density mass lesion without contrast enhancement in the pineal region. A CT cisternography demonstrated the lesion as a filling defect area on the image produced immediately after the emergent V-P shunt, and a filling area 24 hours later. The lesion was of signal intensity on T-1 weighted MR image and of high signal intensity on T-2 weighted MR image, equal to CSF intensity. These radiological findings were compatible with an arachnoid cyst in the quadrigeminal cistern, so we performed the excision of both anterior and posterior cyst walls using the occipital tentorial approach. However, the histology of the cyst wall was not compatible with that of an arachnoid cyst, showing neuroepithelial-like cell lining with positive staining for cytokeratine. The postoperative follow-up on MRI was continued for 31 months. An MRI performed 9 days after the first operation showed, compared with the gray matter, iso-signal intensity area and high signal intensity area on T-1 weighted image. At first, we thought this was because of bleeding of the pineal gland brought on by the operative maneuver. However, the mixed intensity lesion shown on T-1 weighted images gradually expanded and distorted, and finally showed the typical MR images for a teratoma. The operative findings using the occipital transtentorial approach were typical for a teratoma.(ABSTRACT TRUNCATED AT 250 WORDS)
报告了一例16个月大婴儿的成熟松果体畸胎瘤罕见病例,其具有有趣的影像学表现。该患者因全身性惊厥被转诊至我们的诊所。CT扫描显示松果体区有明显脑积水和一个无强化的低密度肿块病变。CT脑池造影显示,在紧急脑室-腹腔分流术后立即生成的图像上,病变为充盈缺损区,24小时后为充盈区。该病变在T-1加权磁共振图像上呈等信号强度,在T-2加权磁共振图像上呈高信号强度,与脑脊液信号强度相等。这些影像学表现与四叠体池蛛网膜囊肿相符,因此我们采用枕下小脑幕入路切除了囊肿的前后壁。然而,囊肿壁的组织学表现与蛛网膜囊肿不符,显示神经上皮样细胞内衬,细胞角蛋白染色阳性。术后对磁共振成像进行了31个月的随访。首次手术后9天进行的磁共振成像显示,与灰质相比,T-1加权图像上有等信号强度区和高信号强度区。起初,我们认为这是手术操作导致的松果体出血。然而,T-1加权图像上显示的混合强度病变逐渐扩大并变形,最终显示出畸胎瘤的典型磁共振图像。采用枕下小脑幕入路的手术所见为典型的畸胎瘤表现。(摘要截断于250字)