Vasil'ev V N, Grabovskaia E A, Chir'ev A I, Shumilov S P, Travkov Iu A
Patol Fiziol Eksp Ter. 1993 Jan-Feb(1):19-21.
The authors studied duodenal myoelectric activity and the activity of trypsin, alpha 1-antitrypsin, alpha 2-macroglobulin, alpha-amylase, and kallikrein after 15-minute occlusion of the hepatic portal vein. The correlation was found between the activity of alpha 1-antitrypsin and the phases of the myoelectrical complex. It is concluded that the discharge of pancreatic proteases during an operative trauma may underlie the pathogenesis of postoperative inhibition of intestinal peristalsis.
作者研究了肝门静脉闭塞15分钟后十二指肠的肌电活动以及胰蛋白酶、α1-抗胰蛋白酶、α2-巨球蛋白、α-淀粉酶和激肽释放酶的活性。发现α1-抗胰蛋白酶的活性与肌电复合波的各阶段之间存在相关性。得出的结论是，手术创伤期间胰腺蛋白酶的释放可能是术后肠道蠕动抑制发病机制的基础。
