Sugiyama A
Department of Radiology, Shizuoka Saiseikai General Hospital.
Nihon Igaku Hoshasen Gakkai Zasshi. 1994 Jul 25;54(8):767-75.
Fifty-one patients with vertebral metastasis were studied by MR imaging. T1 and T2*-gradient field echo (FE) sequences (0.5 Tesla) were performed in all patients. Primary sites were the lung (10 cases), breast (9 cases), colorectal area (9 cases), prostate (7 cases), liver (4 cases) and others. Of the 618 vertebrae evaluated, 315 had metastatic abnormalities, 241 (76.5%) of which showed low intensity on T1-weighted images. High intensity lesions on T2* weighted images were seen in 301 vertebrae (95.5%). Concerning the distribution of metastatic lesions, lumbosacral vertebrae were the most common sites, with the thoracic spine second in frequency. No significant difference was noticed between these primary sites. A total of 244 metastatic lesions occupied most of the vertebral body, 49 of which were accompanied with epidural tumors. Seventy-one small lesions were considered early metastasis, two-thirds of which were located in the metaphysis of vertebrae. No epidural tumors were seen in this group. These findings suggest that the main route for metastatic cancer cells to the vertebrae is the systemic circulation rather than the vertebral venous system.
对51例椎体转移瘤患者进行了磁共振成像（MR）研究。所有患者均采用T1和T2 *梯度场回波（FE）序列（0.5特斯拉）进行检查。原发部位包括肺（10例）、乳腺（9例）、结直肠区（9例）、前列腺（7例）、肝脏（4例）及其他部位。在评估的618个椎体中，315个存在转移异常，其中241个（76.5%）在T1加权图像上表现为低信号。301个椎体（95.5%）在T2 *加权图像上可见高信号病变。关于转移瘤的分布，腰骶椎是最常见的部位，胸椎其次。这些原发部位之间未发现显著差异。共有244个转移瘤占据了大部分椎体，其中49个伴有硬膜外肿瘤。71个小病变被认为是早期转移，其中三分之二位于椎体的干骺端。该组未见硬膜外肿瘤。这些发现提示，转移癌细胞至椎体的主要途径是体循环而非椎静脉系统。
