Greer G G, Milazzo F H
Can J Microbiol. 1975 Jun;21(6):877-83. doi: 10.1139/m75-130.
The addition of Pseudomonas aeruginosa KCIIR LPS to respiring mitochondria stimulated the rate of substrate oxidation, reduced the respiratory control ratio, stimulated oxygen uptake in state 4, and released the inhibition imposed upon state 3 by atractyloside. It was concluded that LPS acted as an uncoupler of oxidative phosphorylation and that it produced effects similar to those observed with the classical uncoupler 2,4-dinitrophenol.
向进行呼吸作用的线粒体中添加铜绿假单胞菌KCIIR脂多糖，刺激了底物氧化速率，降低了呼吸控制率，刺激了状态4下的氧气摄取，并解除了苍术苷对状态3的抑制作用。得出的结论是，脂多糖起到了氧化磷酸化解偶联剂的作用，并且它产生的效应与经典解偶联剂2,4-二硝基苯酚所观察到的效应相似。
