[细菌性脑膜炎中的脑脊液]

[The cerebrospinal fluid in bacterial meningitis].

作者信息

de Campos C E, Santos N N, Takahashi M N, Kawamura I E, Damião S V, Kushnaroff T M, de Campos E P

机构信息

Hospital Emiílio Ribas, São Paulo, Brasil.

出版信息

Rev Soc Bras Med Trop. 1994 Apr-Jun;27(2):87-91. doi: 10.1590/s0037-86821994000200006.

DOI:10.1590/s0037-86821994000200006

PMID:8073157

Abstract

Samples of 1815 cerebrospinal fluid (CSF) were studied in a meningitis outbreak during 1989 in São Paulo, Brazil. Neisseria meningitis 56% with 44% type B, Haemophilus influenzae 17%, from which 72% in children (days to 3-year-old) and Streptococcus pneumoniae 14% from which 60% in children (day to 1-year-old) of 443 (24%) of all strains. Cytochemistry study showed: purulent or turbidity aspects in 70 to 79% positive bacterioscopy or culture of CSF; white cells count > 500/mm3; glucose < 45 mg/dl; protein > 90 mg/dl in 90% of all patients. We concluded that: CSF prognostic factors: (aspect and cytochemistry) were correlated with bacterial meningitis. Bacterioscopy and positive cultures were correlated to NM, SP and HI isolation from these patients (Goodman Test).

摘要

1989年在巴西圣保罗的一次脑膜炎暴发期间，对1815份脑脊液样本进行了研究。脑膜炎奈瑟菌占56%，其中B型占44%；流感嗜血杆菌占17%，其中72%为儿童（出生至3岁）；肺炎链球菌占14%，其中60%为儿童（出生至1岁），占所有菌株的443株（24%）。细胞化学研究显示：在脑脊液细菌学检查或培养呈阳性的患者中，70%至79%呈现脓性或浑浊外观；白细胞计数>500/mm³；葡萄糖<45mg/dl；90%的患者蛋白质>90mg/dl。我们得出结论：脑脊液的预后因素（外观和细胞化学）与细菌性脑膜炎相关。细菌学检查和阳性培养结果与从这些患者中分离出的脑膜炎奈瑟菌、肺炎链球菌和流感嗜血杆菌相关（古德曼检验）。