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[动脉内区域化疗在Ⅲ期胃癌综合治疗中的应用]

[Intra-arterial regional chemotherapy in the combined treatment of stage-III cancer of the stomach].

作者信息

Zyrianov B N, Makarkin N A, Tikhonov V I, Tuzikov S A

出版信息

Vopr Onkol. 1993;39(1-3):40-4.

PMID:8073674
Abstract

The report discusses a method of long-term catheterization of the celiac artery by lumbo-transaortal access. Intraarterial regional chemotherapy with 5-fluorouracil was administered to 56 cases of gastric cancer, stage III, before and after surgery. A significant drop in postoperative complication rate from 47.8 +/- 6% after surgery to 16.0 +/- 4% after combination treatment was recorded. During two years after operation, metastases and recurrences were registered in II out of 52 patients receiving intraarterial chemotherapy (21. +/- 5%), as compared with 34 out of 58 (58.6 +/- 6%) in controls without chemotherapy.

摘要

该报告讨论了一种通过经腰-经主动脉途径对腹腔动脉进行长期导管插入术的方法。对56例III期胃癌患者在手术前后进行了5-氟尿嘧啶动脉内区域化疗。记录到术后并发症发生率从术后的47.8±6%显著降至联合治疗后的16.0±4%。在术后两年期间,接受动脉内化疗的52例患者中有11例(21.±5%)出现转移和复发,而未接受化疗的对照组58例中有34例(58.6±6%)出现转移和复发。

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