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[饮食在高危人群癌前病变预防和治疗中的作用]

[The role of diet in the prevention and treatment of precancerous conditions in the risk groups].

作者信息

Sotnikova E N, Drakina L V, Isaev V A, Ibragimov V R, Bikbov T M, Lisianskaia I B, Soloveva N P, Aleksandrova L M

出版信息

Vopr Pitan. 1993 Jul-Sep(4):41-4.

PMID:8073693
Abstract

The authors studied feasibility of using flavours, particularly, agent M-1 containing basic nutrients of antipromotor action in available form and fish oil containing fatty omega-3 acids as well as natural vitamin E for correction of homeostasis in patients with gastrointestinal precancer. 142 patients at risk to develop gastrointestinal cancer received diets for 6 months by 2-month cycles: M-1 daily in a dose 15-50 g, fish oil in a dose 10-30 ml. Control subjects did not receive the diets. 6 months after the treatment start the test subjects exhibited regression of the disease in 36.6% the cases versus 14.1% in the controls. It is concluded that the above dietetic scheme promotes correction of antioxidant insufficiency and stabilization of cellular membranes in patients with mucosal dysplasia.

摘要

作者研究了使用调味剂,特别是以可用形式含有抗促癌作用基本营养素的M-1制剂、含有ω-3脂肪酸的鱼油以及天然维生素E来纠正胃肠道癌前病变患者体内稳态的可行性。142名有患胃肠道癌风险的患者按2个月周期接受了6个月的饮食:每天服用剂量为15 - 50克的M-1制剂,服用剂量为10 - 30毫升的鱼油。对照组未接受这些饮食。治疗开始6个月后,试验组36.6%的病例病情出现消退,而对照组为14.1%。得出的结论是,上述饮食方案有助于纠正黏膜发育异常患者的抗氧化不足并稳定细胞膜。

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引用本文的文献

1
Omega 3 fatty acids for prevention and treatment of cardiovascular disease.欧米伽3脂肪酸用于预防和治疗心血管疾病。
Cochrane Database Syst Rev. 2004 Oct 18(4):CD003177. doi: 10.1002/14651858.CD003177.pub2.