Terskikh I I, Abramova L N, L'vov S D, Gromashevskiĭ V L, Skvortsova T M, Akhnazarova V D
Vopr Virusol. 1993 Jan-Feb;38(1):39-43.
Neurotropic properties of Leiv 12724 Ax and Leiv 13004 Ax strains were demonstrated by inoculation of green monkeys, Syrian hamsters and white mice using different routes. The strain Leiv 13004 Ax showed more marked pathogenicity for monkeys and rodents producing lesions in all parts of the brain: temporal, frontal, occipital, cerebellar, medulla oblongata and spinal cord where productive vasculitis, perivascular infiltrations, hemorrhages, and dystrophy of nerve cells were observed. In hamsters, the strains Leiv 13004 Ax and Leiv 12724 Ax inoculated subcutaneously produced latent infection with long-term virus carrier state.
通过不同途径接种绿猴、叙利亚仓鼠和小白鼠，证明了Leiv 12724 Ax和Leiv 13004 Ax菌株的嗜神经特性。Leiv 13004 Ax菌株对猴子和啮齿动物表现出更明显的致病性，在大脑各部位（颞叶、额叶、枕叶、小脑、延髓和脊髓）产生病变，观察到有增殖性血管炎、血管周围浸润、出血和神经细胞营养不良。在仓鼠中，皮下接种Leiv 13004 Ax和Leiv 12724 Ax菌株产生了潜伏感染，并伴有长期病毒携带状态。
