• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

联合化疗后儿童晚期肝肿瘤的可切除性

Resectability of advanced liver tumours in children after combination chemotherapy.

作者信息

Munro F D, Simpson E, Azmy A F

机构信息

Department of Paediatric Surgery, Royal Hospital for Sick Children, Glasgow.

出版信息

Ann R Coll Surg Engl. 1994 Jul;76(4):253-6.

PMID:8074387
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2502261/
Abstract

Five patients with locally advanced or metastatic liver tumours were treated at the Royal Hospital for Sick Children between 1983 and 1992 by preoperative combination chemotherapy and subsequent complete resection of the residual liver tumour. Chemotherapy was generally well tolerated with few significant adverse effects. Tumour resection was accomplished by lobectomy in three cases and an extended lobectomy in the remaining two. All five children are currently well and free of disease at a mean follow-up of 36 months.

摘要

1983年至1992年间，皇家儿童医院对5例局部晚期或转移性肝肿瘤患者进行了术前联合化疗，随后对残留的肝肿瘤进行了完整切除。化疗总体耐受性良好，几乎没有明显的不良反应。3例患者通过叶切除术完成肿瘤切除，其余2例进行了扩大叶切除术。5名儿童目前情况良好，平均随访36个月无疾病复发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84f9/2502261/813bae6b26bb/annrcse01590-0047-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84f9/2502261/3d7c016d2b7b/annrcse01590-0047-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84f9/2502261/813bae6b26bb/annrcse01590-0047-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84f9/2502261/3d7c016d2b7b/annrcse01590-0047-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84f9/2502261/813bae6b26bb/annrcse01590-0047-b.jpg

相似文献

1
Resectability of advanced liver tumours in children after combination chemotherapy.联合化疗后儿童晚期肝肿瘤的可切除性
Ann R Coll Surg Engl. 1994 Jul;76(4):253-6.
2
[Differentiated treatment protocols for high- and standard-risk hepatoblastoma--an interim report of the German Liver Tumor Study HB99].[高风险和标准风险肝母细胞瘤的差异化治疗方案——德国肝脏肿瘤研究HB99的中期报告]
Klin Padiatr. 2003 May-Jun;215(3):159-65. doi: 10.1055/s-2003-39375.
3
Advanced hepatoblastoma: successful liver resection following preoperative chemotherapy.晚期肝母细胞瘤：术前化疗后成功进行肝切除术
Trop Gastroenterol. 2004 Jan-Mar;25(1):32-3.
4
Midterm results with hepatectomy after preoperative chemotherapy in hepatoblastoma.肝母细胞瘤术前化疗后肝切除的中期结果
Pediatr Surg Int. 2005 May;21(5):364-8. doi: 10.1007/s00383-005-1381-1. Epub 2005 Apr 19.
5
The influence of preoperative chemotherapy and surgical technique in the treatment of hepatoblastoma--a report from the German Cooperative Liver Tumour Studies HB 89 and HB 94.术前化疗和手术技术对肝母细胞瘤治疗的影响——来自德国肝脏肿瘤协作研究HB 89和HB 94的报告
Eur J Pediatr Surg. 2002 Aug;12(4):255-61. doi: 10.1055/s-2002-34484.
6
Efficiency and toxicity of ifosfamide, cisplatin and doxorubicin in the treatment of childhood hepatoblastoma. Study Committee of the Cooperative Paediatric Liver Tumour Study HB89 of the German Society for Paediatric Oncology and Haematology.异环磷酰胺、顺铂和阿霉素治疗儿童肝母细胞瘤的疗效与毒性。德国儿科肿瘤学和血液学学会儿童肝脏肿瘤合作研究HB89委员会。
Eur J Cancer. 1997 Jul;33(8):1243-9. doi: 10.1016/s0959-8049(97)00095-6.
7
Surgical view of the treatment of patients with hepatoblastoma: results from the first prospective trial of the International Society of Pediatric Oncology Liver Tumor Study Group.肝母细胞瘤患者治疗的手术视角：国际小儿肿瘤学会肝脏肿瘤研究组首个前瞻性试验的结果
Cancer. 2002 Feb 15;94(4):1111-20.
8
Effect of neoadjuvant chemotherapy on resectability of stage III and IV hepatoblastoma.新辅助化疗对 III 期和 IV 期肝母细胞瘤可切除性的影响。
Br J Surg. 2015 Jan;102(1):108-13. doi: 10.1002/bjs.9681. Epub 2014 Oct 28.
9
Resectability and tumor response after preoperative chemotherapy in hepatoblastoma treated by the Japanese Study Group for Pediatric Liver Tumor (JPLT)-2 protocol.日本小儿肝脏肿瘤研究组（JPLT）-2方案治疗的肝母细胞瘤术前化疗后的可切除性及肿瘤反应
J Pediatr Surg. 2016 Dec;51(12):2053-2057. doi: 10.1016/j.jpedsurg.2016.09.038. Epub 2016 Sep 17.
10
Preoperative transcatheter selective arterial chemoembolization in treatment of unresectable hepatoblastoma in infants and children.术前经导管选择性动脉化疗栓塞治疗婴幼儿不可切除的肝母细胞瘤
Cardiovasc Intervent Radiol. 2008 Nov-Dec;31(6):1117-23. doi: 10.1007/s00270-008-9373-x. Epub 2008 Jun 17.

引用本文的文献

1
Conversion of unresectable to resectable hepatoblastoma and long-term follow-up study.不可切除性肝母细胞瘤转化为可切除性肝母细胞瘤及长期随访研究
World J Surg. 1995 Nov-Dec;19(6):814-6. doi: 10.1007/BF00299776.
2
Cytoreduction and sequential resection for surgically verified unresectable hepatocellular carcinoma: evaluation with analysis of 72 patients.经手术证实不可切除的肝细胞癌的细胞减灭术及序贯切除术：72例患者分析评估
World J Surg. 1995 Nov-Dec;19(6):784-9. doi: 10.1007/BF00299771.

本文引用的文献

1
Preoperative chemotherapy for hepatoblastoma in children: report of six cases.儿童肝母细胞瘤的术前化疗：6例报告
J Pediatr Surg. 1980 Aug;15(4):517-22. doi: 10.1016/s0022-3468(80)80765-2.
2
Chemotherapy, radiotherapy, and hepatic lobectomy for hepatoblastoma in an infant: report of a survival.婴儿肝母细胞瘤的化疗、放疗及肝叶切除术：一例生存报告
Surgery. 1970 Aug;68(2):383-8.
3
Primary liver tumors in children: comparison of CT and MR imaging.儿童原发性肝脏肿瘤：CT与磁共振成像的比较
Radiology. 1988 Dec;169(3):727-32. doi: 10.1148/radiology.169.3.2847233.
4
Preoperative chemotherapy in 'unresectable' hepatoblastoma.“不可切除的”肝母细胞瘤的术前化疗
J Pediatr Surg. 1989 Jan;24(1):24-8; discussion 29. doi: 10.1016/s0022-3468(89)80294-5.
5
Hepatoblastoma and hepatocarcinoma in children: analysis of a series of 29 cases.儿童肝母细胞瘤和肝癌：29例病例系列分析
J Pediatr Surg. 1986 May;21(5):424-9. doi: 10.1016/s0022-3468(86)80513-9.
6
Treatment of disseminated hepatoblastoma involving bilateral lobes.双侧叶弥漫性肝母细胞瘤的治疗。
J Pediatr Surg. 1990 Dec;25(12):1253-5. doi: 10.1016/0022-3468(90)90522-b.
7
Effectiveness and toxicity of cisplatin and doxorubicin (PLADO) in childhood hepatoblastoma and hepatocellular carcinoma: a SIOP pilot study.顺铂和阿霉素（PLADO）治疗儿童肝母细胞瘤和肝细胞癌的有效性及毒性：一项国际小儿肿瘤学会（SIOP）的试点研究
Med Pediatr Oncol. 1991;19(3):199-203. doi: 10.1002/mpo.2950190310.
8
Liver transplantation for hepatoblastoma. The American experience.肝母细胞瘤的肝移植。美国的经验。
Ann Surg. 1991 Feb;213(2):118-21. doi: 10.1097/00000658-199102000-00004.
9
Aggressive excision of pulmonary metastases is warranted in the management of childhood hepatic tumors.
J Pediatr Surg. 1991 Sep;26(9):1082-5; discussion 1085-6. doi: 10.1016/0022-3468(91)90678-m.
10
The surgical management of children with incompletely resected hepatic cancer is facilitated by intensive chemotherapy.
J Pediatr Surg. 1991 Sep;26(9):1074-80; discussion 1080-1. doi: 10.1016/0022-3468(91)90677-l.