Blanco A, Méndez A, Carrasco L, Bautista M J, Sierra M A
Department of Anatomy and Pathological Anatomy, Faculty of Veterinary, University of Córdoba, Spain.
Histol Histopathol. 1994 Apr;9(2):251-8.
In this work we have studied the morphology and evolution of Clara cells in the bronchiolar mucosa of lungs from 63 Swiss mice foetuses that were classified into three groups according to age (14, 16 and 18 days). A control group composed of 21 15-day-old Swiss mice was also studied. The most salient feature of the Clara cells observed was the occurrence of two types of secretory granules and a large smooth endoplasmic reticulum. On the other hand, the Clara cells of the control group had a single secretory granule. Clara cells thus seem to take part in bronchiolar metabolism, as they were quite abundant in the early foetal groups and diminished as birth approached. This cell decrease was confirmed by the control group (15-day-old mice), the bronchioles of which contained scant cells and numerous ciliated cells.
在这项研究中，我们对63只瑞士小鼠胎儿肺细支气管黏膜中的克拉拉细胞的形态和演变进行了研究，这些胎儿根据年龄分为三组（14天、16天和18天）。还对由21只15日龄瑞士小鼠组成的对照组进行了研究。观察到的克拉拉细胞最显著的特征是出现了两种类型的分泌颗粒和大量光滑内质网。另一方面，对照组的克拉拉细胞只有一种分泌颗粒。因此，克拉拉细胞似乎参与细支气管代谢，因为它们在胎儿早期组中相当丰富，随着出生临近而减少。对照组（15日龄小鼠）证实了这种细胞减少，其细支气管中细胞稀少，有大量纤毛细胞。
