Sayin A, Bozkurt A K, Tüzün H, Vural F S, Erdog G, Ozer M
Department of Thoracic and Cardiovascular Surgery, Istanbul University Cerrahpasa Medical Faculty, Turkey.
Cardiovasc Surg. 1993 Aug;1(4):377-80.
Buerger's disease (thromboangiitis obliterans) is a rare peripheral vascular disease that usually affects young male smokers. It is characterized by multiple occlusions distal to the knee and elbow. Although rarely encountered in this condition, major arterial occlusions can be corrected by arterial revascularization. The hospital records of 216 patients (214 men and 2 women) with Buerger's disease were reviewed retrospectively, 142 (66%) between 1 and 120 (mean(s.d.) 72.8(24)) months after diagnosis. Of these patients 21 had had an arterial revascularization; 183 lumbar and 20 thoracic sympathectomies had been performed. In 30 of the patients a total of 29 minor and four major amputations had been performed. In appropriate cases arterial reconstruction provides better healing of ischaemic lesions. Although vasomotor tone is usually normalized in 2 weeks to 6 months after sympathectomy, the temporary increase in blood flow is often sufficient to heal ischaemic lesions during this period.
血栓闭塞性脉管炎是一种罕见的周围血管疾病,通常影响年轻男性吸烟者。其特征是膝部和肘部远端出现多处闭塞。尽管在这种情况下很少见,但主要动脉闭塞可通过动脉血运重建来纠正。对216例血栓闭塞性脉管炎患者(214例男性和2例女性)的医院记录进行了回顾性研究,其中142例(66%)在诊断后1至120个月(平均(标准差)72.8(24)个月)。这些患者中,21例接受了动脉血运重建;进行了183例腰交感神经切除术和20例胸交感神经切除术。30例患者共进行了29例小截肢和4例大截肢。在适当的病例中,动脉重建可使缺血性病变更好地愈合。尽管交感神经切除术后血管运动张力通常在2周内至6个月恢复正常,但在此期间血流量的暂时增加通常足以使缺血性病变愈合。