Vanleeuw P, Calozet Y, Eucher P, Rubay J, Schoevaerdts J C
Department of Cardiovascular and Thoracic Surgery, Catholic University of Louvain (UCL), University Clinic of Mont Godinne UCL, Yvoir, Belgium.
Cardiovasc Surg. 1993 Dec;1(6):654-6.
Thirty-five patients (10 men and 25 women) with a preoperative diagnosis of cardiac myxoma have undergone cardiac surgery since 1964 at the University of Louvain. The mean age of the patients was 49 (range 20-75) years. The most commonly encountered symptoms were: dyspnoea 49%; thoracic pain 26%; cough and peripheral embolism 17% each; stroke and preoperative atrial fibrillation 14% each; flutter 11%; expectoration, acute pulmonary oedema, syncope and transient ischaemic attack 6% each; and pulmonary embolism 3%. The different locations were: left atrium 66%; right atrium 26%; both atria 3%; right ventricle 3%: and retrohepatic vena cavae 3%. Septal implantation was found in 66%. Histological examination confirmed 28 myxomas but three 'tumours' were thrombi, two haemangiomas, one rhabdomyosarcoma and one liposarcoma. The follow-up has now reached 2829 months with an average of 81 months per patient (range 0-342 months). Three patients died early (9%) and there were four late deaths (11%). No cases were familial. Surgical resection is the correct treatment for cardiac myxomas and gives good long-term results.
自1964年以来,卢万大学有35例术前诊断为心脏黏液瘤的患者接受了心脏手术,其中男性10例,女性25例。患者的平均年龄为49岁(范围20 - 75岁)。最常见的症状为:呼吸困难占49%;胸痛占26%;咳嗽和周围栓塞各占17%;中风和术前房颤各占14%;扑动占11%;咳痰、急性肺水肿、晕厥和短暂性脑缺血发作各占6%;肺栓塞占3%。不同的部位为:左心房占66%;右心房占26%;双侧心房占3%;右心室占3%;肝后腔静脉占3%。66%的病例为间隔植入。组织学检查确诊黏液瘤28例,但有3个“肿瘤”为血栓,2个为血管瘤,1个为横纹肌肉瘤,1个为脂肪肉瘤。目前随访已达2829个月,平均每位患者81个月(范围0 - 342个月)。3例患者早期死亡(9%),4例患者晚期死亡(11%)。无家族性病例。手术切除是治疗心脏黏液瘤的正确方法,且能取得良好的长期效果。