Transfer of a genetic form of epilepsy in the chicken by embryonic brain grafts.
作者信息
Teillet M A, Guy N T, Schuler B, Le Gal La Salle G, Batini C, Le Douarin N M, Naquet R
机构信息
Institut d'Embryologie Cellulaire et Moléculaire, CNRS-UMRC 9924, Collège de France, Nogent-sur-Marne, France.
出版信息
C R Acad Sci III. 1993 Sep;316(9):1164-76.
PMID:8076211
Abstract
The genetic photosensitive epilepsy of the Fayoumi chickens was transferred to normal chickens by grafting, in situ, on the 2nd day of incubation, the prosencephalic and mesencephalic vesicles from epileptic embryos. Such chimeras displayed typical interictal EEG and developed intermittent light stimulation-induced seizures phenotypically and electrically similar to the epileptic strain seizures.
摘要
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