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[切尔诺贝利核电站事故后5年去污参与者的细胞遗传学检查结果]

[Results of cytogenetic examination of participants in the decontamination after the accident at the Chernobyl nuclear power station, 5 years later].

作者信息

Snigireva G P, Liubchenko P N, Shevchenko V A, Novitskaia N N, Borisova N M, Dubinina E B, Maslennikova V G

出版信息

Gematol Transfuziol. 1994 May-Jun;39(3):19-21.

PMID:8076786
Abstract

Results of the cytogenetic investigation on the Chernobyl accident decontamination participants, 5 years after the accident, have been disclosed. Cytogenetic analysis was performed on circulating blood lymphocytes, using a standard cultivation technique. Differences were detected between control group and decontamination participants on frequency of aberrant cells and aberrations of chromosome type in peripheral blood lymphocytes. Maximal cytogenetic effect on this data was detected in persons, who had worked between May and August 1986. On the base of cytogenetic investigation data, the authors proposed to form high-risk groups, including oncologic risk groups, which need a profound dynamic investigation.

摘要

事故发生5年后,对切尔诺贝利事故去污参与者进行的细胞遗传学调查结果已公布。采用标准培养技术,对循环血液淋巴细胞进行细胞遗传学分析。在对照组和去污参与者之间,检测到外周血淋巴细胞中异常细胞的频率和染色体类型畸变存在差异。根据这些数据,在1986年5月至8月期间工作的人员中检测到最大的细胞遗传学效应。基于细胞遗传学调查数据,作者建议组建高危人群组,包括肿瘤风险人群组,这些人群需要进行深入的动态调查。

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