Gupta V
Department of Pediatrics, Banaras Hindu University, Varanasi.
Indian Pediatr. 1993 Oct;30(10):1175-9.
Twenty four children with bacterial meningitis were studied prospectively to ascertain the incidence, type and severity of hearing loss. The incidence of sensorineural hearing loss was 20.8%. Patients with hearing loss were followed-up audiologically for six months to find out the progress of hearing impairment. Of the five patients with sensorineural hearing loss only one showed partial recovery while the other three did not show any improvement. Of the five patients with sensorineural hearing loss only one showed partial recovery while the other three did not show any improvement. One patient was lost to follow-up, therefore, recovery was not known. The degree of hearing loss varied form mild to moderate. Antibiotic treatment and laboratory data were analysed to identify the high risk factors predisposing to hearing impairment. The presence of low CSF sugar level, high protein at the initial lumbar puncture and presence of neurological deficits was associated with a significantly higher risk of hearing loss. However, the nature of antibiotic therapy, duration of illness, age and sex of the patients were not significant risk factors in the development of hearing impairment.
对24例细菌性脑膜炎患儿进行了前瞻性研究,以确定听力损失的发生率、类型和严重程度。感音神经性听力损失的发生率为20.8%。对有听力损失的患者进行了为期6个月的听力随访,以了解听力障碍的进展情况。在5例感音神经性听力损失患者中,只有1例有部分恢复,而其他3例没有任何改善。在5例感音神经性听力损失患者中,只有1例有部分恢复,而其他3例没有任何改善。有1例患者失访,因此,恢复情况不明。听力损失程度从轻度到中度不等。分析了抗生素治疗情况和实验室数据,以确定易导致听力障碍的高危因素。脑脊液低糖水平、初次腰椎穿刺时高蛋白以及存在神经功能缺损与听力损失风险显著较高相关。然而,抗生素治疗的性质、病程、患者年龄和性别并非听力障碍发生的显著危险因素。