Christo G G, Shenoy V, Matthai J, Shivananda P G, Venkatesh A
Department of Pediatrics, Kasturba Medical College and Hospital, Manipal, Karnataka.
Indian Pediatr. 1993 Dec;30(12):1413-6.
Twenty-six neonates were diagnosed to have acinetobacter sepsis during 1986-90, representing 6.5% of all cases of bacteriologically proven sepsis. Of these 19 neonates were low birth weight (LBW) 12 were small for gestational age (SGA). Nineteen neonates had early-onset sepsis. The male to female ratio was 9:17. The hematological profile was suggestive of sepsis in 17 cases. All infants had clinical evidence of multi system infection. Eleven babies died; the cases-fatality rate was 42.3%. Only 15/25 culture isolates were sensitive to gentamicin and resistance to other antibiotics was even more frequent. Acinetobacter was cultured from other sites: eye swabs, skin pustules and umbilical catheter tips. Environmental nursery surveillance cultures done during the study period yielded Acinetobacter once from a crib, but no cases of sepsis occurred around that time. The epidemiological features of this organism illustrate the value of vigilance and precautionary measures.
1986年至1990年期间，26例新生儿被诊断为不动杆菌败血症，占所有细菌学证实败血症病例的6.5%。其中，19例新生儿为低体重儿（LBW），12例为小于胎龄儿（SGA）。19例新生儿发生早发型败血症。男女比例为9:17。17例患儿的血液学检查结果提示败血症。所有婴儿均有多系统感染的临床证据。11例婴儿死亡；病死率为42.3%。仅15/25株培养分离菌对庆大霉素敏感，对其他抗生素的耐药更为常见。不动杆菌还从其他部位培养出来：眼拭子、皮肤脓疱和脐导管尖端。研究期间进行的环境病房监测培养仅从一张婴儿床中分离出一次不动杆菌，但当时周围未发生败血症病例。该病原体的流行病学特征说明了警惕和预防措施的重要性。
