Gustafson B W
Big Horn Animal Clinic, Sheridan, WY 82801.
J Am Vet Med Assoc. 1994 Jun 15;204(12):1922-3.
A 2-year-old Collie-type dog with lethargy, tachycardia, tachypnea, and muscle tremors was examined 10 hours after the dog had bitten into an inhalation canister containing the beta 2-adrenergic agonist, terbutaline sulfate. Electrocardiographic findings (ventricular premature contractions and paroxysmal ventricular tachycardia) were consistent with excessive adrenergic activity resulting from terbutaline toxicosis. Serum terbutaline concentration was similar to that reported in human beings with terbutaline toxicosis. The dog did not respond to initial treatment with fluids and lidocaine administered IV, but rapid resolution of signs and conversion to normal sinus rhythm was achieved after IV infusion of propranolol.
一只2岁的柯利牧羊犬在咬开一个装有β2-肾上腺素能激动剂硫酸特布他林的吸入罐10小时后接受检查，它表现出嗜睡、心动过速、呼吸急促和肌肉震颤。心电图检查结果（室性早搏和阵发性室性心动过速）与硫酸特布他林中毒导致的肾上腺素能活动过度相符。血清特布他林浓度与报道的硫酸特布他林中毒人类患者相似。这只狗对静脉注射液体和利多卡因的初始治疗没有反应，但在静脉输注普萘洛尔后，症状迅速缓解并恢复为正常窦性心律。
