取代的1-[(5-硝基糠叉基)氨基]-4-咪唑啉-2-酮。
Substituted 1-[(5-nitrofurfurylidene)amino]-4-imidazolin-2-ones.
作者信息
Snyder H R, Freedman R
出版信息
J Med Chem. 1975 May;18(5):524-6. doi: 10.1021/jm00239a019.
PMID:807733
Abstract
A series of 1-[(5-nitrofurfurylidene)amino]-4-imidazolin-2-ones has been prepared. A new synthesis of 4-alkyl-1-[(5-nitrofurfurylidene)amino]-4-imidazolin-2-ones involving the oxidative ring closure of 5-nitro-2-furaldehyde 2-(2-hydroxyethylalkyl)semicarbazones is described. The in vitro testing of the compounds against a variety of bacteria is reported.
摘要
已经制备了一系列1-[(5-硝基糠叉基)氨基]-4-咪唑啉-2-酮。描述了一种涉及5-硝基-2-糠醛2-(2-羟乙基烷基)氨基脲氧化闭环反应的4-烷基-1-[(5-硝基糠叉基)氨基]-4-咪唑啉-2-酮的新合成方法。报道了这些化合物对多种细菌的体外测试结果。
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