Koehn K A, Burnette M M, Stark C
Marquette General Hospital.
J Behav Ther Exp Psychiatry. 1993 Dec;24(4):331-41. doi: 10.1016/0005-7916(93)90058-5.
Four individuals with frequent recurrences of genital herpes simplex virus (HSV) were trained in Applied Relaxation (AR). Participants included in the research had been diagnosed with herpes at least 1 year prior to the study, experienced six or more outbreaks annually, and were not taking antiviral medications. The experiment employed a multiple baseline across subjects design. Participants maintained daily diaries of the frequency, duration and severity of herpes activity from baseline until a minimum of 3 months posttreatment. Treatment consisted of 10 individual AR sessions. Pretraining and posttraining frontalis electromyographic activity measures of subjects' ability to relax during rest and to apply the relaxation skill during stressful role plays were obtained. All subjects reported pretreatment to posttreatment reductions in herpes frequency. These changes were statistically significant across all subjects as a group and individually for three of the four subjects. These results suggest that AR is an effective technique for reducing recurrent HSV infection.
对四名复发性单纯疱疹病毒(HSV)生殖器感染患者进行了渐进性放松训练(AR)。参与该研究的受试者在研究开始前至少已被诊断出患有疱疹1年,每年经历6次或更多次发作,且未服用抗病毒药物。实验采用多基线受试者间设计。参与者从基线开始直至治疗后至少3个月,每天记录疱疹活动的频率、持续时间和严重程度。治疗包括10次个体渐进性放松训练课程。获得了受试者在休息时放松以及在压力角色扮演中应用放松技巧能力的训练前和训练后额肌肌电图活动测量结果。所有受试者均报告疱疹发作频率从治疗前到治疗后有所降低。作为一个整体,所有受试者的这些变化具有统计学意义,并且四名受试者中有三名个体的变化具有统计学意义。这些结果表明,渐进性放松训练是一种减少复发性HSV感染的有效技术。