使用旋毛虫幼虫和包虫囊液抗原对实验性旋毛虫病进行免疫接种。
Immunization against experimental trichinosis using T. spiralis larvae and hydatid fluid antigens.
作者信息
el-Ganayni G A, el-Shazly A M, el-Naggar H M
机构信息
Department of Parasitology, Faculty of Medicine, Mansoura University, Egypt.
出版信息
J Egypt Soc Parasitol. 1994 Aug;24(2):341-7.
Immunization of mice against T. spiralis infection using T. spiralis larval glycoproteins as homogenous antigen and crude hydatid fluid as heterogenous antigen showed a marked reduction in larvae burden and a significant rise of serum IgE in immunized mice infected with T. spiralis larvae as compared with control group. More reduction was observed with immunization with homogenous T. spiralis larval antigen compared with heterogenous hydatid fluid antigen. The reduction in larval burden with rise of serum IgE begins after the third week of immunization.
用旋毛虫幼虫糖蛋白作为同源抗原以及粗制包虫液作为异源抗原对小鼠进行抗旋毛虫感染免疫，结果显示，与对照组相比，感染旋毛虫幼虫的免疫小鼠体内幼虫负荷显著降低，血清IgE显著升高。与异源包虫液抗原相比，用同源旋毛虫幼虫抗原免疫观察到更多的幼虫负荷降低。免疫第三周后开始出现幼虫负荷降低以及血清IgE升高的情况。
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