Miura T, Nakamura R, Horii E
Chukyou University, Toyota City, Japan.
J Hand Surg Br. 1994 Jun;19(3):350-4. doi: 10.1016/0266-7681(94)90088-4.
The clinical features of 53 cases of intercalated hypoplasia and 113 cases of distal aplasia are reviewed and compared with each other and with 129 cases of syndactyly. Tri-, di- and mono-phalangeal symbrachydactyly, and adactyly with nubbin digits are consecutive anomalies. Transverse deficiency may result if the mesenchyme is damaged severely, and if damage is mild and formation has continued, intercalated transverse deficiency may occur. Webbing in symbrachydactyly may result from failure of the apical ectodermal ridge under the influence of damaged mesenchyme.
回顾了53例节间发育不全和113例远端发育不全的临床特征，并将它们相互比较，同时与129例并指畸形进行了比较。三指、二指和单指短指畸形以及带有残指的无指畸形是连续的异常情况。如果间充质受到严重损伤，可能会导致横向缺损；如果损伤较轻且发育仍在继续，则可能会出现节间横向缺损。并指畸形中的蹼可能是由于受损间充质影响下顶端外胚层嵴发育失败所致。
