Wang X, Stoltz J F
URA CNRS 875, Laboratoire d'Energétique et de Mécanique théorique et appliquée, Vandoeuvre-les-Nancy.
J Mal Vasc. 1994;19(2):137-41.
The authors studied the global transport of red blood cells (RBC) in a stationary cylindrical tube flow. The human blood was considered as homogeneous fluid. For geometric and dynamic conditions fixed, the quantity of transported RBC was calculated using different models of constitutive equation: i) Newtonian model with apparent viscosity measured at 128 sec-1; ii) Landel's model for rigidified RBC suspension; iii) three non-Newtonian models (Casson law, power law and a relationship of Sisko). We showed that there was an optimum hematocrit for every model for which the quantity of transported RBC was maximum. The values of optimum hematocrit obtained for the non-Newtonian models varied in function of the tube radius and the pressure drop. It was equally observed that the optimum hematocrit was very small when the red blood cells were rigid. These theoretical results merit experimental studies and open the way to investigations of mechanical transport of RBC (global oxygen transport) under different types of flow conditions.
作者研究了在固定圆柱形管流中红细胞（RBC）的整体传输。将人体血液视为均匀流体。在固定几何和动力学条件下，使用不同的本构方程模型计算传输的RBC数量：i）在128秒⁻¹下测量表观粘度的牛顿模型；ii）用于硬化RBC悬浮液的兰德尔模型；iii）三种非牛顿模型（卡森定律、幂律和西斯科关系）。我们表明，每个模型都存在一个最佳血细胞比容，此时传输的RBC数量最大。非牛顿模型获得的最佳血细胞比容值随管半径和压降而变化。同样观察到，当红细胞刚性时，最佳血细胞比容非常小。这些理论结果值得进行实验研究，并为研究不同类型流动条件下RBC的机械传输（整体氧气传输）开辟了道路。
