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食管闭锁:20世纪90年代的高危人群。

Oesophageal atresia: at-risk groups for the 1990s.

作者信息

Spitz L, Kiely E M, Morecroft J A, Drake D P

机构信息

Department of Surgery, Hospital for Sick Children, London, England.

出版信息

J Pediatr Surg. 1994 Jun;29(6):723-5. doi: 10.1016/0022-3468(94)90354-9.

Abstract

The authors analyzed the outcome for 357 infants with oesophageal atresia and 15 with H-type tracheoesophageal fistula treated from 1980 through 1992. Survival according to Waterston risk categories was 99% for group A, 95% for group B, and 71% for group C. Presently, with optimal management, virtually all infants in groups A and B should survive. When examining the risk factors in the infants who died, two criteria were found to be important predictors of outcome: birth weight of less than 1,500 g and the presence of major congenital cardiac disease. A new classification for predicting outcome in oesophageal atresia is proposed: group I: birth weight > or = 1,500 g, without major cardiac disease, survival 97% (283 of 293); group II: birth weight < 1,500 g, or major cardiac disease, survival 59% (41 of 70); and group III: birth weight < 1,500 g, and major cardiac disease, survival 22% (2 of 9).

摘要

作者分析了1980年至1992年期间接受治疗的357例食管闭锁婴儿和15例H型气管食管瘘婴儿的治疗结果。根据沃特斯顿风险分类,A组的生存率为99%,B组为95%,C组为71%。目前,通过优化管理,A组和B组的几乎所有婴儿都应能存活。在检查死亡婴儿的风险因素时,发现两个标准是结果的重要预测指标:出生体重低于1500克和存在严重先天性心脏病。提出了一种预测食管闭锁预后的新分类方法:I组:出生体重≥1500克,无严重心脏病,生存率97%(293例中的283例);II组:出生体重<1500克,或有严重心脏病,生存率59%(70例中的41例);III组:出生体重<1500克,且有严重心脏病,生存率22%(9例中的2例)。

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