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[干扰素治疗慢性丙型肝炎——使用逻辑回归模型进行多变量分析评估干扰素治疗效果的预测因素]

[Interferon treatment of chronic hepatitis C--assessment of predictive factors to the effect of interferon treatment using multivariate analysis with the logistic regression model].

作者信息

Terada M, Ikegami F

机构信息

Department of Gastroenterology, Kanto-Teishin Hospital.

出版信息

Nihon Rinsho. 1994 Jul;52(7):1774-7.

PMID:8078201
Abstract

We treated 156 chronic hepatitis C patients with alpha-interferon (IFN) and assessed the response rate and the predictive factors to the effect of IFN treatment. Complete response (CR) rate was 39.1%, and CR with serum HCV-RNA disappearance rate was 29%. CR to IFN treatment was dependent on HCV serotype and serum HCV-RNA. Patients of serotype II and low serum HCV-RNA were effective to IFN treatment.

摘要

我们用α干扰素治疗了156例慢性丙型肝炎患者,并评估了对干扰素治疗效果的反应率和预测因素。完全缓解(CR)率为39.1%,血清HCV-RNA消失的CR率为29%。对干扰素治疗的CR取决于HCV血清型和血清HCV-RNA。II型血清型和低血清HCV-RNA的患者对干扰素治疗有效。

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