Nakajima T, Ota K, Ishihara S, Wakabayashi K, Nishi M
Division of Gastrointestinal Surgery, Cancer Institute Hospital.
Gan To Kagaku Ryoho. 1994 Aug;21(11):1768-74.
A total of 8,993 cases of gastric cancer which were undergone gastrectomy at Cancer Institute Hospital, Tokyo were subjected to the multi-variate analysis of prognostic factors in gastric cancer. Relative ratio of hazard risk indicated the rank of importance in prognostic factors as the following order: Hepatic metastasis, radicality of surgery, macroscopic tumor type, serosal involvement, number of involved lymph node, and grade of lymph node metastasis. Difference in the results of analysis was observed between mono- and multi-variate analysis in the following categories: site of primary lesion, type of resection, and chemotherapy. These results suggested the importance of multimodality therapy to achieve the absolute curative surgery for advanced cancer, and also the importance of multi-variate analysis for the proper evaluation of prognostic factors.
对东京癌症研究所医院接受胃切除术的8993例胃癌患者进行了胃癌预后因素的多变量分析。风险相对比表明预后因素的重要性排序如下：肝转移、手术根治性、肿瘤大体类型、浆膜受累情况、受累淋巴结数量及淋巴结转移分级。单变量分析和多变量分析在以下方面的分析结果存在差异：原发灶部位、切除类型及化疗。这些结果表明多模式治疗对于实现晚期癌症的绝对根治性手术很重要，同时多变量分析对于正确评估预后因素也很重要。
