Randhawa V S, Sharma V K, Malhotra V, Vij J C
Department of Microbiology, Maulana Azad Medical College.
Arch Pathol Lab Med. 1994 Sep;118(9):891-4.
We present a morphometric analysis of findings from a histopathologic study of duodenal giardiasis in relation to the trophozoite count in the duodenal aspirate. Of 30 patients with giardiasis whose conditions were studied, a mean trophozoite count of 10(3)/mL or greater was found in 21, and a mean trophozoite count of less than 10(3)/mL was found in nine--these two types of trophozoite counts in these 30 patients represented the acute phase (group 1) and the clearance phase (group 2) of giardiasis, respectively. Group 1 patients had a low mean villus height that was significantly less than that found in the control subjects. Group 2 patients had a high mean crypt depth that was significantly greater than that found in the control subjects. Partial villus atrophy was seen in only seven of the group 1 patients, including five with villus epithelial cell lesions. Groups 1 and 2 showed minor differences of an inflammatory response that was significantly greater than that shown in the control subjects.
我们针对十二指肠贾第虫病组织病理学研究的结果进行了形态计量分析，该分析与十二指肠抽吸物中的滋养体计数相关。在接受病情研究的30例贾第虫病患者中，21例患者的平均滋养体计数为每毫升10³个或更多，9例患者的平均滋养体计数低于每毫升10³个——这30例患者的这两种滋养体计数类型分别代表贾第虫病的急性期（第1组）和清除期（第2组）。第1组患者的平均绒毛高度较低，显著低于对照组受试者。第2组患者的平均隐窝深度较高，显著高于对照组受试者。仅在第1组的7例患者中观察到部分绒毛萎缩，其中5例有绒毛上皮细胞病变。第1组和第2组显示出炎症反应的微小差异，该炎症反应显著大于对照组受试者所显示的炎症反应。
