右旋糖酐铁经胎盘的转运。
Transfer of iron-dextran across the placenta.
作者信息
Djaldetti M, Notti I, Fishman P, Bessler H
出版信息
Acta Haematol. 1975;53(5):292-9. doi: 10.1159/000208195.
In pregnant mice. 55Fe-labeled iron-dextran (Imferon) is transferred across the placenta. It was detected in the bone marrow, liver, spleen and peripheral blood of the pregnant animal, as well as in the embryonic liver erythroid precursors and peripheral blood. Uptake by liver and peripheral blood cells of pregnant anemic mice and by liver erythroid precursors of anemic embryos was significantly higher than in normal control animals. Electron-microscopic examination revealed that the iron deposits in the embryonic liver erythroid precursors had the same structure as the injected Imferon.
在怀孕小鼠中，55Fe标记的右旋糖酐铁（Imferon）可穿过胎盘。在怀孕动物的骨髓、肝脏、脾脏和外周血中以及胚胎肝脏红系前体细胞和外周血中均检测到该物质。怀孕贫血小鼠的肝脏和外周血细胞以及贫血胚胎的肝脏红系前体细胞对其摄取量显著高于正常对照动物。电子显微镜检查显示，胚胎肝脏红系前体细胞中的铁沉积物与注射的Imferon具有相同的结构。
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