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色甘酸二钠(2%)鼻喷雾剂治疗季节性变应性鼻炎的开放性评估

An open assessment of lomudal (disodium cromoglycate) (2 per cent) nasal spray in seasonal allergic rhinitis.

作者信息

Löfkvist T, Svensson G

出版信息

Acta Allergol. 1975 Jul;30(2-3):89-95. doi: 10.1111/j.1398-9995.1975.tb01332.x.

Abstract

The effect of Disodium cromoglycate (Lomudal, Intal) on allergic rhinitis, given as a solution in a nasal spray, was studied in 23 adult volunteers with grass pollen allergy, none of whom were having hyposensitization therapy. The trial was carried out as an open assessment during the months of June and July, 1972. Two squirts (1.6 mg D.S.C.G.) from the nasal spray were applied to each nostril every 3 h throughout the day. In 80 per cent of subjects the treatment was successful. No side effects were noted, but five patients expressed a preference for a preparation that could be administered at less frequent intervals.

摘要

在23名对草花粉过敏的成年志愿者中,研究了以鼻喷雾剂形式给药的色甘酸钠(Lomudal、Intal)对过敏性鼻炎的疗效,这些志愿者均未接受脱敏治疗。该试验于1972年6月和7月进行,为开放性评估。全天每3小时向每个鼻孔喷两下(1.6毫克色甘酸钠)。80%的受试者治疗成功。未观察到副作用,但有5名患者表示更喜欢给药间隔时间更长的制剂。

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