Marshak R H, Hazzi C, Lindner A E, Maklansky D
Am J Gastroenterol. 1975 Jul;64(1):59-73.
Recent advances in immunology have permitted recognition of a group of patients who have gastrointestinal manifestations as part of an immunoglobulin deficency syndrome. Such immunoglobulin deficiency may be primary or may be secondary to a variety of diseases. We have classified and described the small bowel roentgen features associated with the various immunoglobulin deficiency syndromes as follows: 1. the sprue pattern, as seen in hypogammaglobulinemic sprue and in Ig-A deficient sprue; 2. multiple nodular defects; 3. inflammatory changes secondary to giardiasis, associated with immune deficiency diseases; 4. thickening of the small intestinal folds, as seen in the plasma cell dyscrasias, lymphoma, intestinal lymphangiectasia and amyloidosis.
免疫学的最新进展使人们能够识别出一组患有胃肠道表现的患者，这些表现是免疫球蛋白缺乏综合征的一部分。这种免疫球蛋白缺乏可能是原发性的，也可能继发于多种疾病。我们已对与各种免疫球蛋白缺乏综合征相关的小肠X线特征进行了分类和描述，如下：1. 口炎性腹泻型，见于低丙种球蛋白血症性口炎性腹泻和Ig-A缺乏性口炎性腹泻；2. 多个结节状缺损；3. 继发于贾第虫病的炎症改变，与免疫缺陷疾病相关；4. 小肠皱襞增厚，见于浆细胞发育异常、淋巴瘤、肠淋巴管扩张症和淀粉样变性。
