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良性前列腺增生症患者的血清激素水平

Serum hormone levels in benign prostatic hyperplasia.

作者信息

Sköldefors H, Blomstedt B, Carlström K

出版信息

Scand J Urol Nephrol. 1978;12(2):111-4. doi: 10.3109/00365597809179975.

DOI:10.3109/00365597809179975
PMID:80820
Abstract

The peripheral serum levels of FSH, LH, testosterone and total estrone (sum of free + conjugated estrone, mainly estrone sulphate) were determined in 20 patients with benign prostatic hyperplasia (BPH) aged 59--79 years and in 49 healthy men aged 58--79 years. There were no significant differences in the levels of FSH, LH and testosterone. The level of total estrone was significantly higher in the BPH group (p less than 0.05). The results are in accordance with our previous study on the urinary estrogen excretion in BPH and give additional support to the hypotheses concerning a role of the estrogens in the etiology of BPH.

摘要

对20例年龄在59至79岁的良性前列腺增生(BPH)患者及49例年龄在58至79岁的健康男性测定了外周血中促卵泡生成素(FSH)、促黄体生成素(LH)、睾酮及总雌酮(游离雌酮+结合雌酮之和,主要为硫酸雌酮)的水平。FSH、LH及睾酮水平无显著差异。BPH组总雌酮水平显著更高(p<0.05)。这些结果与我们之前关于BPH患者尿雌激素排泄的研究一致,并进一步支持了雌激素在BPH病因中起作用的假说。

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引用本文的文献

1
Serum steroid and sex hormone-binding globulin concentrations and the risk of incident benign prostatic hyperplasia: results from the prostate cancer prevention trial.血清类固醇和性激素结合球蛋白浓度与良性前列腺增生发病风险:前列腺癌预防试验结果
Am J Epidemiol. 2008 Dec 15;168(12):1416-24. doi: 10.1093/aje/kwn272. Epub 2008 Oct 21.
2
Studies on the role of sex-hormone-binding globulin (SHBG) in benign prostatic hypertrophy in men. I. Clinical research.性激素结合球蛋白(SHBG)在男性良性前列腺增生中作用的研究。I. 临床研究。
Int Urol Nephrol. 1984;16(2):141-7. doi: 10.1007/BF02082778.
3
Spontaneous benign prostatic hyperplasia in the beagle. Age-associated changes in serum hormone levels, and the morphology and secretory function of the canine prostate.
比格犬自发性良性前列腺增生。血清激素水平的年龄相关性变化以及犬前列腺的形态和分泌功能。
J Clin Invest. 1983 May;71(5):1114-23. doi: 10.1172/jci110861.