Sköldefors H, Blomstedt B, Carlström K
Scand J Urol Nephrol. 1978;12(2):111-4. doi: 10.3109/00365597809179975.
The peripheral serum levels of FSH, LH, testosterone and total estrone (sum of free + conjugated estrone, mainly estrone sulphate) were determined in 20 patients with benign prostatic hyperplasia (BPH) aged 59--79 years and in 49 healthy men aged 58--79 years. There were no significant differences in the levels of FSH, LH and testosterone. The level of total estrone was significantly higher in the BPH group (p less than 0.05). The results are in accordance with our previous study on the urinary estrogen excretion in BPH and give additional support to the hypotheses concerning a role of the estrogens in the etiology of BPH.
对20例年龄在59至79岁的良性前列腺增生(BPH)患者及49例年龄在58至79岁的健康男性测定了外周血中促卵泡生成素(FSH)、促黄体生成素(LH)、睾酮及总雌酮(游离雌酮+结合雌酮之和,主要为硫酸雌酮)的水平。FSH、LH及睾酮水平无显著差异。BPH组总雌酮水平显著更高(p<0.05)。这些结果与我们之前关于BPH患者尿雌激素排泄的研究一致,并进一步支持了雌激素在BPH病因中起作用的假说。