Halberg F, Cornélissen G, Bingham C, del Pozo F, Arredondo M T, Otsuka K, Quadens O, Breus T, Rapoport S, Komarov F
University of Minnesota, Minneapolis 55455.
J Clin Pharmacol. 1994 Jun;34(6):552-7. doi: 10.1002/j.1552-4604.1994.tb02006.x.
A remote computerized health care (telehygiene) system for space travel includes monitoring devices and pharmaceuticals aimed at the optimization of health and the environment. Early risk indicators are provided by dynamic characteristics of rhythms of several frequencies describing variation inside the physiologic range. These rhythm characteristics, assessed as one goes, can be updated and compacted as data accumulate by the use of chronobiologic software that resolves anticipated components of lower and lower frequency, thus providing summaries of data at intervals of differing length. At any time, harbingers of risk, including characteristics of circannual rhythms, can be retrieved in an instant. On their basis, early preventive action can be instituted for risk lowering and for delivery of timed treatment when needed. Preventive or curative health care in space and terrestrial spin-offs are the more effective the more of the chronome (time-structure) is resolved.
一种用于太空旅行的远程计算机化医疗保健(远程卫生保健)系统包括监测设备和药品,旨在优化健康状况和环境。早期风险指标由描述生理范围内变化的几种频率的节律动态特征提供。随着数据的积累,通过使用能够解析越来越低频率的预期成分的生物钟软件,可以对这些节律特征进行评估、更新和压缩,从而以不同的时间间隔提供数据摘要。在任何时候,包括年节律特征在内的风险先兆都可以立即检索到。在此基础上,可以采取早期预防措施来降低风险,并在需要时进行定时治疗。在太空以及地面衍生应用中,对时间结构解析得越多,预防性或治疗性医疗保健就越有效。