Sadhukhan B, Roychowdhury U, Banerjee P, Sen S
Department of Endocrinology and Metabolism, IPGME & R and SSKM Hospital, Calcutta.
J Indian Med Assoc. 1994 Apr;92(4):115-7.
Sixty-seven diabetic patients and 12 normal subjects were selected for a clinical study with an indigenous herbal product. The study consisted of 2 phases. In phase 1 study out of 25 diabetics (both insulin dependent and non-insulin dependent) only those in the age group of 41-50 years ie, 11 cases showed lowering of mean high blood sugar level in all samples from 1/2 an-hour to 2 hours with the test drug containing guar gum, methi, tundika and mesha shringi. But in phase 2 study there was lowering of blood sugar level with the test drug and with 2 of its constituents ie, guar gum and methi when used separately in 42 non-insulin dependent diabetics. While there was some blood sugar level lowering effect with guar gum and methi when used separately in 12 normal subjects in phase 2 study, but that was not the same observed with the test drug. The results of this study indicate the efficacy of the product as an adjuvant.
67名糖尿病患者和12名正常受试者被选来参与一项使用一种本土草药产品的临床研究。该研究包括两个阶段。在第一阶段研究中，从25名糖尿病患者（包括胰岛素依赖型和非胰岛素依赖型）中，仅年龄在41至50岁的11名患者，其所有样本（从半小时到2小时）的平均高血糖水平在使用含有瓜尔胶、葫芦巴、tundika和mesha shringi的受试药物后有所降低。但在第二阶段研究中，受试药物及其两种成分（即瓜尔胶和葫芦巴）在42名非胰岛素依赖型糖尿病患者中单独使用时都能降低血糖水平。在第二阶段研究中，瓜尔胶和葫芦巴在12名正常受试者中单独使用时也有一定的降血糖作用，但与受试药物观察到的情况不同。这项研究的结果表明该产品作为佐剂的有效性。
