Kuckuck L, Chhina G S, Manchanda S K
Indian J Physiol Pharmacol. 1975 Jan-Mar;19(1):20-7.
In 17 cases of vasectomy, the external diameter of vas deferens was found to be 2.07 +/- .27 mm (Mean +/- S.D.) with a range from 1.7 to 2.8 mm. The internal diameters were 0.93 +/- 0.13 at 5 g and 1.24 +/- 0.16 mm at 100 g insertion force applied to the measuring cone, with lumen ranges from 0.7 to 1.2 and 1.0 to 1.7 mm, respectively. The left-right variations in the same inidividual were of a similar order as between different individuals. Measurements in 6-10 kg rhesus monkeys revealed an internal vas diameter around 0.6 mm with the measuring cone only eased in. At considerably high pressure the vas could be distended to show an internal diameter around 1 mm. The external diameters ranged from 1.5 to 2 mm. Local application to the vas in vivo or in vitro of alpha or beta adrenergic blocking agents, and sodium nitrate had no appreciable effects on the diameters. Three types of valves were developed and tested. The tap-like and the rotary valves were not satisfactorily leak-proof. But the valve with stop-cock mechanism was found to be satisfactory. It was further tested by examining the ejaculate obtained by the method of electro-ejaculation after implanting the valve in the monkey vas. The stop-cock valve is being proposed as a working model for producing reversible vas-occlusion.
在17例输精管结扎术中，发现输精管外径为2.07±0.27毫米（均值±标准差），范围为1.7至2.8毫米。在向测量圆锥体施加5克和100克插入力时，内径分别为0.93±0.13毫米和1.24±0.16毫米，管腔范围分别为0.7至1.2毫米和1.0至1.7毫米。同一个体的左右差异与不同个体之间的差异相似。对6至10千克恒河猴的测量显示，仅轻轻插入测量圆锥体时输精管内径约为0.6毫米。在相当高的压力下，输精管可扩张至内径约为1毫米。外径范围为1.5至2毫米。在体内或体外对输精管局部应用α或β肾上腺素能阻滞剂以及硝酸钠，对管径没有明显影响。开发并测试了三种类型的瓣膜。龙头状瓣膜和旋转瓣膜的防漏效果不理想。但发现带旋塞机构的瓣膜令人满意。在将瓣膜植入猴输精管后，通过检查电射精法获得的射精进一步对其进行了测试。现提出将旋塞瓣膜作为产生可逆性输精管阻塞的工作模型。
