[Polymorphism locus Pi (alpha1-antitrypsin) of residents in the Poznan province].

Locus Pi (Pi-protease inhibitor) polymorphism in the Polish population was determined with isoelectrofocusing human blood proteins in super-thin agarose gel. There were 13 phenotypes of alpha 1-antitrypsin in the tested 631 sera collected from blood donors and inhabitants of both Poznań city and Poznań province. An incidence of locus Pi alleles in the Polish population was determined: PiM1 = 0.7464; PiM2 = 0.1656; PiM3 = 0.0570; PiS = 0.0142; PiZ = 0.015; PiVar = 0.0016. Out of rare Pi variants PiI = 0.0008 and PiR = 0.0008 were identified. The obtained results were compared with those for the European populations.