Fengler S A, Pearl R K
Division of Colon and Rectal Surgery, Cook County Hospital, Chicago, IL 60612.
Semin Surg Oncol. 1994 May-Jun;10(3):200-7. doi: 10.1002/ssu.2980100308.
Surgery is the primary mode of therapy for colorectal cancer. Advances beyond exteriorization began to appear at the end of the nineteenth century. The antibiotic era brought on more advances. Dogma abounds with respect to the technical aspects of surgery for colon and rectal cancer and few randomized, prospective trials have been done to evaluate the importance of these techniques. Firmly established are the techniques of resection of lymphatic drainage of tumors, en bloc resection of invaded structures, and obtaining at least 2 cm margins of rectal cancers. Radical lymph node dissection, luminal ligation, oophorectomy, and the "No-Touch Technique" are discussed. Despite the paucity of irrefutable scientific data to support many of the described surgical techniques, differences in outcome between surgeons suggest that technique is important. There is great need for randomized, prospective trials to evaluate the multitude of techniques described for the surgical treatment of colorectal cancer.
手术是结直肠癌的主要治疗方式。19世纪末开始出现超越肠外置术的进展。抗生素时代带来了更多进展。关于结肠癌和直肠癌手术的技术方面存在诸多教条,很少有随机前瞻性试验来评估这些技术的重要性。肿瘤淋巴引流切除、受累结构整块切除以及直肠癌至少切缘2厘米的技术已牢固确立。讨论了根治性淋巴结清扫、腔内结扎、卵巢切除术和“不接触技术”。尽管缺乏确凿的科学数据来支持许多所描述的手术技术,但外科医生之间的疗效差异表明技术很重要。非常需要进行随机前瞻性试验来评估所描述的用于结直肠癌手术治疗的众多技术。