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[梅多斯综合征:产后心肌病]

[Meadows syndrome: puerperal cardiomyopathy].

作者信息

Fadouach S, Matar N, Meziane M, Tahiri A, Chraibi N

机构信息

Service de Cardiologie, CHU Ibn Rochd, Casablanca, Maroc.

出版信息

Rev Fr Gynecol Obstet. 1994 Jun;89(6):335-6.

PMID:8085105
Abstract

This retrospective study concerns six cases of gravido-puerperal cardiomyopathy. These six cases account for 18% of all cases of non-obstructive cardiomyopathy (NOCM) affecting women in general and 67% of NOCM in women of childbearing age. Mean age was 28.5 with a range of 18 to 39. Reported risk factors include poor socio-economic conditions, multiparity, twin pregnancies and anemia. The clinical picture is that of cardiac failure, most often congestive (83.3%), with a systolic murmur of functional mitral incompetence (50%) and atypical chest pain (50%). The ECG is invariably abnormal, without specific signs. The high incidence of repolarisation disturbances is a fairly special feature. Echocardiography is the technique of choice, enabling detection, diagnosis and study of ventricular function, which is an important factor in prognostic evaluation. Medical treatment is based upon a combination of rest, salt-free diet, diuretics, digitalis and vasodilators. The etiology remains unknown and the prognosis is severe despite cases of complete recovery.

摘要

这项回顾性研究涉及6例妊娠-产后心肌病患者。这6例患者占所有非梗阻性心肌病(NOCM)女性患者的18%,占育龄期女性NOCM患者的67%。平均年龄为28.5岁,范围在18至39岁之间。报告的危险因素包括社会经济状况差、多产、双胎妊娠和贫血。临床表现为心力衰竭,最常见的是充血性心力衰竭(83.3%),伴有功能性二尖瓣关闭不全的收缩期杂音(50%)和非典型胸痛(50%)。心电图总是异常的,但无特异性体征。复极异常的高发生率是一个相当特殊的特征。超声心动图是首选技术,能够检测、诊断并研究心室功能,而心室功能是预后评估的一个重要因素。药物治疗基于休息、无盐饮食、利尿剂、洋地黄和血管扩张剂的联合应用。病因仍然不明,尽管有完全康复的病例,但预后仍然很差。

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