Wang M Y
Cell Electrophysiology Laboratory, Wannan Medical College, Wuhan.
Sheng Li Xue Bao. 1994 Feb;46(1):95-9.
Intracellular recordings of antidromically identified sympathetic preganglionic neurons (SPNs) were made in thoracolumbar spinal cord slices from neonate rats (7-16 days). In the SPNs population, a 7-20 mV long-lasting afterhyperpolarization (11-AHP) lasting for 1 to 10 s following spike potential could be recorded in part of the neurons and the 11-AHPs was usually preceded by a fast component lasting shorter than 400 ms. With decrease of membrane resistance during 11-AHP, membrane potential-dependent property was observed and the calculated reversal potential was -90 to -100 mV. The results indicate that the 11-AHPs are effective in the control of firing frequency of SPNs.
在新生大鼠（7 - 16日龄）的胸腰段脊髓切片中，对经逆向鉴定的交感神经节前神经元（SPNs）进行了细胞内记录。在SPNs群体中，部分神经元在动作电位后可记录到持续1至10秒、幅度为7 - 20 mV的长时程超极化后电位（11 - AHP），且11 - AHP之前通常有一个持续时间短于400毫秒的快速成分。在11 - AHP期间，随着膜电阻降低，观察到膜电位依赖性特性，计算得到的反转电位为 - 90至 - 100 mV。结果表明，11 - AHP对控制SPNs的放电频率有效。
