Iwanami A, Sugiyama A, Kuroki N, Toda S, Kato N, Nakatani Y, Horita N, Kaneko T
Department of Psychiatry, Tokyo Metropolitan Matsuzawa Hospital, Japan.
Acta Psychiatr Scand. 1994 Jun;89(6):428-32. doi: 10.1111/j.1600-0447.1994.tb01541.x.
To examine the clinical characteristics of methamphetamine (MAP) psychosis in Japan, we evaluated 104 patients with MAP psychosis (80 men and 24 women) admitted to the closed psychiatric units of Tokyo Metropolitan Matsuzawa Hospital between 1988 and 1991. There has recently been a steep increase in the number of admissions for MAP psychosis, reflecting the growth of the epidemic of MAP abuse in Japan. Although more than half of the patients were discharged within one month, 16 patients were hospitalized for more than 3 months. Most of the patients showed paranoid psychotic state similar to schizophrenia, consistent with previous reports. Despite the abstinence from MAP and antipsychotic medication, psychotic symptoms tended to persist in some of the patients. The etiological role of MAP psychosis in the development of long-lasting psychotic state was discussed.
为研究日本甲基苯丙胺（MAP）所致精神病的临床特征，我们评估了1988年至1991年间入住东京都立松泽医院封闭精神科病房的104例MAP所致精神病患者（80名男性和24名女性）。最近，MAP所致精神病的入院人数急剧增加，这反映出日本MAP滥用情况的增多。虽然超过半数的患者在1个月内出院，但有16名患者住院超过3个月。大多数患者表现出与精神分裂症相似的偏执性精神病状态，这与之前的报道一致。尽管已停用MAP并停止使用抗精神病药物，但部分患者的精神病症状仍有持续。本文讨论了MAP所致精神病在持久精神病状态发展中的病因学作用。
