Hayashi T, Yamauchi A, Hosoda K, Kakehi R
Department of Urology, Tokyo Metropolitan Ohtsuka Hospital.
Hinyokika Kiyo. 1994 Jul;40(7):597-600.
Two adrenal tumors were incidentally discovered in the patients with dawn hypertension. They had no clinical features of Cushing's syndrome. These cases were regarded as pre-Cushing's syndrome by endocrinological evaluation. After adrenalectomy, the adrenal hormone regulation was normalized and dawn hypertension disappeared. Our findings suggest that dawn hypertension is a typical clinical sign of pre-Cushing's syndrome and this syndrome may represent a premature status of Cushing's syndrome.
在黎明高血压患者中偶然发现了两个肾上腺肿瘤。它们没有库欣综合征的临床特征。通过内分泌评估,这些病例被视为库欣综合征前期。肾上腺切除术后,肾上腺激素调节恢复正常,黎明高血压消失。我们的研究结果表明,黎明高血压是库欣综合征前期的典型临床症状,该综合征可能代表库欣综合征的早期状态。