Kamijo T, Sato T, Yanagizawa R, Kishi H
Department of Urology, Tokyo Metropoitan Toshima Hospital.
Hinyokika Kiyo. 1994 Jul;40(7):617-9.
Inverted growth of transitional cell carcinoma in the ureter is reported. A 71-year-old female visited us for right flank pain and gross hematuria. Hematuria from the right ureteral orifice was found by cystoscopy. Intravenous pyelography revealed right hydronephrosis and a filling defect in the right ureter, but the filling defect moved to the lower ureter. Computerized tomographic (CT) scan demonstrated a tiny lesion in the right ureter. Under a tentative diagnosis of right ureteral tumor, flexible fiberoptic ureteroscopy was performed. As a pedunculated tumor with a smooth surface was found, biopsy was performed. Since pathological examination showed malignancy, right nephroureterectomy was performed. Histological diagnosis was transitional cell carcinoma, grade 1. Cancer was covered by normal transitional epithelium, and developed inverted growth. This is a rare case of inverted growth of the transitional cell carcinoma in the ureter.
本文报道了一例输尿管移行细胞癌的内翻性生长病例。一名71岁女性因右侧腰痛和肉眼血尿前来就诊。膀胱镜检查发现右侧输尿管口有血尿。静脉肾盂造影显示右肾积水和右侧输尿管充盈缺损,但充盈缺损移至输尿管下段。计算机断层扫描(CT)显示右侧输尿管有一个微小病变。在初步诊断为右侧输尿管肿瘤后,进行了软性纤维输尿管镜检查。发现一个表面光滑的带蒂肿瘤,遂进行活检。病理检查显示为恶性,于是进行了右侧肾输尿管切除术。组织学诊断为1级移行细胞癌。肿瘤被正常移行上皮覆盖,并呈内翻性生长。这是一例罕见的输尿管移行细胞癌内翻性生长病例。