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直肠内超声与直肠平滑肌肉瘤

Endorectal ultrasound and leiomyosarcoma of the rectum.

作者信息

Wolf O, Glaser F, Kuntz C, Lehnert T

机构信息

Chirurgische Universitätsklinik Heidelberg, Germany.

出版信息

Clin Investig. 1994 May;72(5):381-4. doi: 10.1007/BF00252832.

Abstract

Leiomyosarcomas of the rectum are uncommon neoplasms accounting for fewer than 1% of all malignancies of the colon and rectum. Approximately 215 cases have been described in the literature. Distinction from leiomyoma is often difficult, but regarding dignity is important. The case reported is that of a 68-year-old man in whom a 2.2-cm rectal mass covered by mucosa was diagnosed by rectoscopy and endorectal ultrasound. After treatment by wide local excision the histological specimen revealed a low-grade, highly differentiated leiomyosarcoma. Due to the lack of a large series of this disease, there is disagreement over the therapeutic strategy. At the moment a selective treatment approach seems to be the most frequently advocated. Large tumors and those extending beyond the rectal wall are treated by radical surgical resection. Leiomyosarcomas less than 2.5 cm in size and confined to the bowel wall can be treated by wide local excision. Endosonography can provide exact assessment of tumor size and expansion and is of great value in selecting the appropriate treatment.

摘要

直肠平滑肌肉瘤是一种罕见的肿瘤,占结肠和直肠所有恶性肿瘤的比例不到1%。文献中大约描述了215例病例。与平滑肌瘤进行区分往往很困难,但判断其性质很重要。报道的病例是一名68岁男性,通过直肠镜检查和直肠内超声诊断出一个2.2厘米、被黏膜覆盖的直肠肿物。经过广泛局部切除治疗后,组织学标本显示为低级别、高分化的平滑肌肉瘤。由于缺乏关于这种疾病的大量病例系列研究,对于治疗策略存在分歧。目前,选择性治疗方法似乎是最常被提倡的。大的肿瘤以及那些超出直肠壁的肿瘤通过根治性手术切除进行治疗。直径小于2.5厘米且局限于肠壁的平滑肌肉瘤可以通过广泛局部切除进行治疗。内镜超声检查可以对肿瘤大小和扩展情况进行准确评估,在选择合适的治疗方法方面具有重要价值。

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