Shian W J, Chi C S
Department of Pediatrics, Taichung Veterans General Hospital, Taiwan, R.O.C.
Zhonghua Yi Xue Za Zhi (Taipei). 1994 Jul;54(1):57-61.
The reported annual incidence of acute transverse myelitis (ATM) is 1 per 3.4 million. Because of its rarity, we performed this retrospective clinical investigation.
Hospital records of seven Chinese children with ATM were reviewed thoroughly. The diagnosis of ATM were made clinically with or without neuroimages.
Five males and two females were included, of age from three to sixteen years with a mean of 8.6 years. The common presentations included weakness of lower extremities, acute flaccid paralysis, urinary distention, constipation, hyporeflexia, sensory impairment and paresthesia. Slightly elevated protein level in cerebrospinal fluid was noted. Mycoplasma pneumoniae, varicella/zoster virus and Epstein-Barr virus infections were confirmed serologically in one, one, and two patients, respectively. All patients received supportive treatment. The duration required to reach peak severity from onset of illness ranged from six to forty-eight hours. All but one patient recovered, and one to six months were required to achieve maximum improvement.
Some infectious pathogens may play a role in the pathogenesis of ATM. In general, the prognosis of childhood ATM is good.
据报道，急性横贯性脊髓炎（ATM）的年发病率为每340万人中有1例。由于其罕见性，我们进行了这项回顾性临床研究。
对7例中国儿童ATM患者的医院记录进行了全面回顾。ATM的诊断通过临床诊断，无论有无神经影像学检查。
纳入5例男性和2例女性，年龄3至16岁，平均8.6岁。常见表现包括下肢无力、急性弛缓性麻痹、尿潴留、便秘、反射减退、感觉障碍和感觉异常。脑脊液蛋白水平略有升高。分别在1例、1例和2例患者中血清学确诊肺炎支原体、水痘/带状疱疹病毒和EB病毒感染。所有患者均接受了支持治疗。从发病到达到病情最严重程度所需的时间为6至48小时。除1例患者外，所有患者均康复，达到最大改善需要1至6个月。
某些感染性病原体可能在ATM的发病机制中起作用。一般来说，儿童ATM的预后良好。
