[胃癌中的异位骨化。对一种临床现象的实验性研究（作者译）]
[Heterotopic ossification in cancer of the stomach. An experimental contribution to a clinical phenomenon (author's transl)].
作者信息
Werner B, Dahm K
出版信息
Res Exp Med (Berl). 1975 Sep 24;165(3):219-25. doi: 10.1007/BF01971381.
Heterotopic ossifications are found frequently in rats with nitrosoguanidine-induced carcinomas of the gastric stump. The following steps of differentiation of the desmal ossification in the stump carcinomas are demonstrated: 1. Osteoblasts. 2. Osteoid. 3. Woven Bone reticular network. 4. Lamellar bone. The islands of metaplastic bone cells are predominantly located in the invasive marginal area of the carcinoma of the gastric stump. The histology is similar to that one seen in stomach cancer of men. Therefore, the here described model seems to be suitable for further study of the metaplastic bone formation in the gastrointestinal tract.
在亚硝基胍诱导的胃残端癌大鼠中经常发现异位骨化。以下展示了胃残端癌中真皮骨化的分化步骤：1. 成骨细胞。2. 类骨质。3. 编织骨网状网络。4. 板层骨。化生骨细胞岛主要位于胃残端癌的浸润边缘区域。其组织学与男性胃癌所见相似。因此，这里描述的模型似乎适合进一步研究胃肠道中的化生骨形成。
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