前列腺癌：改善治疗反应及预防并发症的措施

Prostate carcinoma: measures to improve therapeutic response and prevent complications.

作者信息

Green N, Melbye R W, Lipsett J, Kurohara S S, George F W, Cosgrove M, Morrow J

出版信息

Urology. 1975 Sep;6(3):287-90. doi: 10.1016/0090-4295(75)90747-5.

Abstract

Between 1965 and 1973, 80 patients with prostatic carcinoma were treated with definitive supervoltage irradiation; 35 patients received adjuvant estrogens. A favorable tumor response was uniformly observed in patients with less advanced tumors who received a minimum of 6,000 rads tumor dose and adjuvant estrogens. Radiation complications were frequent and severe in patients with locally advanced tumors who had antecedent lower urinary tract surgery and received a minimum of 7,000 rads tumor dose. Complications were less frequent in patients who received adjuvant estrogens, and complications were uncommon and mild in patients who received less than 7,000 rads.

摘要

1965年至1973年间，80例前列腺癌患者接受了根治性超高压放疗；35例患者接受了辅助雌激素治疗。在肿瘤分期较晚、接受至少6000拉德肿瘤剂量和辅助雌激素治疗的患者中，均观察到良好的肿瘤反应。在先前接受过下尿路手术、接受至少7000拉德肿瘤剂量的局部晚期肿瘤患者中，放疗并发症频繁且严重。接受辅助雌激素治疗的患者并发症较少，接受少于7000拉德剂量的患者并发症罕见且轻微。