Markand O N
Department of Neurology, Indiana University School of Medicine, Indianapolis.
J Clin Neurophysiol. 1994 May;11(3):319-42. doi: 10.1097/00004691-199405000-00004.
Brainstem auditory evoked potentials (BAEPs) have obtained widespread clinical application in assessing neurologic and audiologic problems. Seven waves (I-VII) are usually recorded in the first 10 ms following broad-band and high-intensity clicks. Latencies of waves I, III, and V, interpeak latencies of I-III, III-V, and I-V, and the amplitude ratio of wave V to wave I are common parameters evaluated for assessing clinically relevant abnormalities of BAEPs. Usually two-channel recordings are obtained: vertex (Cz) to ipsilateral ear and Cz to contralateral earlobe derivation. Evaluating different components in the two derivations helps their identification, particularly when the BAEPs are abnormal. Several technical and subject-related factors affect the amplitude and latencies of BAEP components besides lesions and dysfunctions involving the peripheral auditory structures and brainstem auditory pathways. BAEPs have maximal clinical utility in evaluating comatose patients, in patients with suspected demyelinating disorders, posterior fossa tumors, or in audiologic evaluation, especially in infants. They are also used for intraoperative monitoring of eighth-nerve and brainstem function during different types of posterior fossa surgery.
脑干听觉诱发电位（BAEPs）在评估神经和听力问题方面已获得广泛的临床应用。在宽带高强度短声刺激后的最初10毫秒内通常可记录到七个波（I - VII）。波I、III和V的潜伏期、I - III、III - V和I - V的峰间潜伏期以及波V与波I的振幅比是评估BAEPs临床相关异常的常用参数。通常获得两通道记录：从头顶（Cz）到同侧耳以及从Cz到对侧耳垂导联。评估两个导联中的不同成分有助于它们的识别，特别是当BAEPs异常时。除了涉及外周听觉结构和脑干听觉通路的病变及功能障碍外，还有几个技术和与受试者相关的因素会影响BAEP成分 的振幅和潜伏期。BAEPs在评估昏迷患者、疑似脱髓鞘疾病患者、后颅窝肿瘤患者或进行听力评估时，尤其是在婴儿中，具有最大的临床效用。它们还用于不同类型后颅窝手术期间对第八神经和脑干功能的术中监测。
