Tanaka S, Hachida M, Kitamura M, Ohtsuka G, Shimamura Y, Nishida H, Endo M, Hashimoto A, Koyanagi H
Department of Cardiovascular Surgery, Tokyo Women's Medical College, Japan.
Nihon Kyobu Geka Gakkai Zasshi. 1994 Jul;42(7):1032-7.
From 1981 to March 1993, 21 patients underwent surgical treatment for infective endocarditis (IE) associated with congenital heart disease (CHD). We evaluated the surgical results with regard to various factors, including microorganisms, pre- and postoperative complications, the correlation between CHD and the infective focus in the valve, the operative methods and surgical results. Underlying CHD included ventricular septal defect (VSD) in 15 (71.5%), persistent ductus arteriosus (PDA) in 2 (9.5%), tetralogy of Fallot (TF) in 2 (9.5%) and incomplete endocardial cushion defect (IECD) in 2 patients (9.5%). Microorganisms were detected in 71.4% of the patients, including streptococcus in 11 patients (52.4%), staphylococcus in 2 (9.5%) and gram-negative bacillin in 2 (9.5%). Embolism or infarction was noted preoperatively in 5 patients (23.8%) and was located in the kidney in 4 patients, the leg in 2, and in the liver and lung in 1 patient each. Among 15 patients with VSD, the lesion of IE was seen on the left side of the heart in 11 patients, on the right side in 3 and on both sides in 1. The PDA and IECD were seen on the left side in 2 patients each, but the IE focus of the 2 patients with TF was on the left side in one and on both sides in the other patient. Aortic valve replacement was performed in 17 patients, mitral valve replacement in 3, tricuspid valve plasty in 2, tricuspid annuloplasty in 1 and pulmonary valve resection in 2 patients. The operative mortality was 4.8% and there were no reoperations or late deaths.(ABSTRACT TRUNCATED AT 250 WORDS)
1981年至1993年3月,21例患有先天性心脏病(CHD)合并感染性心内膜炎(IE)的患者接受了外科治疗。我们评估了手术结果的各种因素,包括微生物、术前和术后并发症、CHD与瓣膜感染灶之间的相关性、手术方法和手术结果。潜在的CHD包括15例(71.5%)室间隔缺损(VSD)、2例(9.5%)动脉导管未闭(PDA)、2例(9.5%)法洛四联症(TF)和2例(9.5%)不完全性心内膜垫缺损(IECD)。71.4%的患者检测到微生物,其中11例(52.4%)为链球菌,2例(9.5%)为葡萄球菌,2例(9.5%)为革兰氏阴性杆菌。术前5例(23.8%)出现栓塞或梗死,4例位于肾脏,2例位于腿部,1例位于肝脏和肺部。15例VSD患者中,11例IE病变位于心脏左侧,3例位于右侧,1例两侧均有。2例PDA和2例IECD患者病变均位于左侧,但2例TF患者中,1例IE病灶位于左侧,另1例两侧均有。17例行主动脉瓣置换术,3例行二尖瓣置换术,2例行三尖瓣成形术,1例行三尖瓣环成形术,2例行肺动脉瓣切除术。手术死亡率为4.8%,无再次手术或晚期死亡。(摘要截断于250字)