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[培养的人皮肤细胞在烧伤治疗中的应用]

[Cultured human skin cells in the treatment of burns].

作者信息

Sarkisov D S, Alekseev A A, Tumanov V P, Glushchenko E V, Morozov S S, Paltsyn A A

出版信息

Khirurgiia (Mosk). 1993 Mar(3):22-7.

PMID:8089964
Abstract

The work discusses the results of experience of long-year's standing of the staff of the Vishnevsky Institute of Surgery in the creation of a biological bandage with the use of cultivated human skin cells. A graft of cultivated human allofibroblasts was used for closure of burn wounds for the first time. Its efficacy was studied in 86 cases of burns. The use of cultivated allofibroblasts is indicated in bordering III ab degree burns and sluggishly healing donor areas formed after autodermoplasty. Study of the efficacy of cultivated allofibroblasts in the treatment of deep burns in combination with dermoplasty with a 1:6 perforated skin autograft are continued. The low cost and technical simplicity of the method allow cultivated fibroblast grafts to be recommended for wide clinical practice.

摘要

该研究探讨了维什涅夫斯基外科研究所工作人员长期以来利用培养的人类皮肤细胞制作生物绷带的经验成果。首次使用培养的人类同种异体成纤维细胞移植物来闭合烧伤创面。对86例烧伤病例进行了其疗效研究。培养的同种异体成纤维细胞适用于Ⅲ度烧伤边界以及自体皮肤移植术后形成的愈合缓慢的供皮区。培养的同种异体成纤维细胞联合1:6多孔自体皮肤移植进行真皮成形术治疗深度烧伤的疗效研究仍在继续。该方法成本低且技术简单,因此推荐将培养的成纤维细胞移植物广泛应用于临床实践。

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