Marapulets L A, Bogatyrev O F
Zh Mikrobiol Epidemiol Immunobiol. 1978 Apr(4):18-23.
In observance of the rules of vaccination and unfavourable anamnesis in the vaccinated serve as the main causes of postvaccinal complications (30 and 22%, respectively). The great majority of complications occurs at the age of 1 to 3 years (76%). In 94% of cases complications are recorded in primarily vaccinated individuals. Solution of such problems as introduction into wide practice of sparing methods of immunization and special scheme of preliminary preparation to the vaccination of weak children and those with conditioned contraindications is necessary for the purpose of prevention of complications; a possibility of using, along with gamma-globulin, of synthetic preparations, and of subjecting older children to primary vaccination for prevention of complications is discussed.
遵守疫苗接种规则以及接种疫苗者不利的既往史是疫苗接种后并发症的主要原因(分别为30%和22%)。绝大多数并发症发生在1至3岁年龄段(76%)。94%的病例中,并发症出现在初次接种疫苗的个体中。为预防并发症,有必要解决一些问题,如广泛采用温和的免疫方法和针对体弱儿童及有条件禁忌证儿童的特殊预接种方案;讨论了除使用丙种球蛋白外,使用合成制剂以及对大龄儿童进行初次接种以预防并发症的可能性。